{"id":721,"date":"2017-03-24T22:04:51","date_gmt":"2017-03-24T13:04:51","guid":{"rendered":"http:\/\/h-crisis.niph.go.jp\/bt\/?page_id=721"},"modified":"2025-09-03T11:25:35","modified_gmt":"2025-09-03T02:25:35","slug":"37detail","status":"publish","type":"page","link":"https:\/\/h-crisis.niph.go.jp\/bt\/other\/37detail\/","title":{"rendered":"\u91cd\u75c7\u71b1\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u5019\u7fa4\uff1aSFTS"},"content":{"rendered":"

\u75c5\u539f\u4f53\u306e\u7279\u5fb4<\/h3>\n

SFTS\u306f\u3001\u30de\u30c0\u30cb\u304c\u5a92\u4ecb\u3059\u308bSFTS\u30a6\u30a4\u30eb\u30b9\uff08SFTSV\uff09\u306b\u3088\u308b\u611f\u67d3\u75c7\u3067\u3042\u308b\u3002SFTSV\u306f**\u30d5\u30a7\u30cc\u30a4\u30a6\u30a4\u30eb\u30b9\u79d1\u30fb\u30d0\u30f3\u30c0\u30a6\u30a4\u30eb\u30b9\u5c5e\uff08Dabie bandavirus\uff09**\u306b\u5206\u985e\u3055\u308c\u308b\u4e00\u672c\u9396RNA\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308b\u3002\u4e3b\u306b\u4e2d\u56fd\u3001\u97d3\u56fd\u3001\u65e5\u672c\u3067\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u65e5\u672c\u3067\u306f2013\u5e74\u306b\u521d\u3081\u3066\u60a3\u8005\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u5f93\u6765\u306f\u897f\u65e5\u672c\u3067\u591a\u304f\u767a\u751f\u3057\u3066\u3044\u305f\u304c\u30012025\u5e748\u6708\u306b\u306f\u5317\u6d77\u9053\u3067\u521d\u306e\u60a3\u8005\u304c\u516c\u5f0f\u306b\u78ba\u8a8d\u3055\u308c\u3001\u6771\u65e5\u672c\u3078\u306e\u62e1\u5927\u306f\u56fd\u306e\u516c\u7684\u6a5f\u95a2\u3067\u3082\u660e\u8a18\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

\u4e2d\u56fd\u3067\u306f\u30d5\u30bf\u30c8\u30b2\u30c1\u30de\u30c0\u30cb\uff08Haemaphysalis longicornis\uff09\u304a\u3088\u3073\u30aa\u30a6\u30b7\u30de\u30c0\u30cb\uff08Rhipicephalus microplus\uff09\u304b\u3089SFTSV\u907a\u4f1d\u5b50\u304c\u691c\u51fa\u3055\u308c\u3066\u3044\u308b\u3002\u4e00\u65b9\u3001\u65e5\u672c\u3067\u306f\u60a3\u8005\u306b\u4ed8\u7740\u3057\u3066\u3044\u305f\u30de\u30c0\u30cb\u3068\u3057\u3066\u30d5\u30bf\u30c8\u30b2\u30c1\u30de\u30c0\u30cb\u3001\u30ad\u30c1\u30de\u30c0\u30cb\u3001\u30bf\u30ab\u30b5\u30b4\u30ad\u30e9\u30e9\u30de\u30c0\u30cb\uff08Amblyomma testudinarium\uff09\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

\u65e5\u672c\u5206\u96e2\u682a\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u3067\u306f\u3001\u4e2d\u56fd\u682a\u3068\u306f\u72ec\u7acb\u3057\u305f\u30af\u30e9\u30b9\u30bf\u30fc\u3092\u5f62\u6210\u3057\u3066\u304a\u308a\u3001\u65e5\u672c\u682a\u306f\u72ec\u81ea\u306e\u9032\u5316\u3092\u9042\u3052\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\uff08\u56f32\uff09\u3002<\/p>\n

\u81ea\u7136\u754c\u3067\u306f\u3001\u30de\u30c0\u30cb\u3068\u54fa\u4e73\u52d5\u7269\u304cSFTSV\u306e\u5bbf\u4e3b\u3067\u3042\u308b\u3002SFTSV\u306f\u6210\u30c0\u30cb\u304b\u3089\u5e7c\u30c0\u30cb\u3078\u7d4c\u5375\u6027\u306b\u4f1d\u642c\u3057\u3001\u3055\u3089\u306b\u30de\u30c0\u30cb\u304b\u3089\u54fa\u4e73\u52d5\u7269\u3078\u611f\u67d3\u3059\u308b\u3002\u9006\u306b\u3001\u611f\u67d3\u3057\u305f\u54fa\u4e73\u52d5\u7269\u304b\u3089\u30de\u30c0\u30cb\u304c\u30a6\u30a4\u30eb\u30b9\u3092\u7372\u5f97\u3059\u308b\u3053\u3068\u3082\u3042\u308b\uff08\u56f33\uff09<\/span>\u3002<\/p>\n

\u611f\u67d3\u7d4c\u8def<\/strong><\/h3>\n

\u4e3b\u306a\u611f\u67d3\u7d4c\u8def\u306f\u3001SFTSV\u3092\u4fdd\u6709\u3059\u308b\u30de\u30c0\u30cb\u306b\u3088\u308b\u523a\u54ac\u3067\u3042\u308b\u3002\u7a7a\u6c17\u611f\u67d3\u306f\u60f3\u5b9a\u3055\u308c\u306a\u3044\u304c\u3001\u8840\u6db2\u30fb\u4f53\u6db2\u3068\u306e\u63a5\u89e6\u306b\u3088\u308a\u30d2\u30c8\u2212\u30d2\u30c8\u611f\u67d3\u304c\u6210\u7acb\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u65e5\u672c\u56fd\u5185\u3067\u3082\u533b\u7642\u5f93\u4e8b\u8005\u306e\u611f\u67d3\u4f8b\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u533b\u7642\u73fe\u5834\u3067\u306f\u6a19\u6e96\u4e88\u9632\u7b56\u304a\u3088\u3073\u63a5\u89e6\u4e88\u9632\u7b56\u3092\u57fa\u672c\u3068\u3057\u3001\u4f53\u6db2\u304c\u98db\u6563\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u51e6\u7f6e\u3067\u306f\u98db\u6cab\u4e88\u9632\u7b56\u3082\u63a8\u5968\u3055\u308c\u308b\u3002<\/p>\n

\n

\u307e\u305f\u3001SFTSV\u306b\u611f\u67d3\u3057\u305f\u52d5\u7269\u304b\u3089\u306e\u611f\u67d3\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u30cd\u30b3\u304b\u3089\u30d2\u30c8\u3078\u306e\u611f\u67d3\u306f\u30b2\u30ce\u30e0\u540c\u4e00\u6027\u3067\u88cf\u4ed8\u3051\u3089\u308c\u305f\u78ba\u5b9f\u306a\u4e8b\u4f8b\u304c\u8907\u6570\u3042\u308a\u3001\u7363\u533b\u7642\u5f93\u4e8b\u8005\u306a\u3069\u3067\u767a\u751f\u3057\u3066\u3044\u308b\u3002\u4e00\u65b9\u3001\u30a4\u30cc\u304b\u3089\u30d2\u30c8\u3078\u306e\u611f\u67d3\u306f\u54ac\u50b7\u5f8c\u306e\u767a\u75c7\u304c\u63a8\u5b9a\u7d4c\u8def\u3068\u3055\u308c\u305f\u75c7\u4f8b\u304c\u3042\u308a\u3001\u300c\u7591\u3044\u4f8b\u300d\u3068\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

\u4e88\u9632<\/strong><\/h3>\n

\u73fe\u5728\u3001\u6709\u52b9\u306a\u30ef\u30af\u30c1\u30f3\u306f\u5b58\u5728\u3057\u306a\u3044\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u30de\u30c0\u30cb\u304c\u591a\u304f\u751f\u606f\u3059\u308b\u8349\u3080\u3089\u3084\u85ea\u306b\u5165\u308b\u969b\u306b\u306f\u3001\u9577\u8896\u3001\u9577\u30ba\u30dc\u30f3\u3001\u5e3d\u5b50\u3001\u624b\u888b\u3092\u7740\u7528\u3057\u3001\u808c\u306e\u9732\u51fa\u3092\u907f\u3051\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u308b\u3002\u30ea\u30b9\u30af\u306f\u6625\u304b\u3089\u79cb\u306b\u304b\u3051\u3066\u9ad8\u304f\u3001\u3068\u304f\u306b\u521d\u590f\u301c\u79cb\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u307e\u305f\u3001\u611f\u67d3\u52d5\u7269\u3068\u306e\u63a5\u89e6\u306b\u3082\u6ce8\u610f\u3092\u8981\u3059\u308b\u3002<\/p>\n

\u4e3b\u306a\u81e8\u5e8a\u50cf<\/h3>\n

\u767a\u71b1\u3001\u6d88\u5316\u5668\u75c7\u72b6\uff08\u5410\u6c17\u3001\u5614\u5410\u3001\u8179\u75db\u3001\u4e0b\u75e2\u306a\u3069\uff09\u3001\u51fa\u8840\u6240\u898b\uff08\u5410\u8840\u3001\u6b6f\u8089\u51fa\u8840\u306a\u3069\uff09\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002\u795e\u7d4c\u75c7\u72b6\u304c\u51fa\u73fe\u3059\u308b\u5834\u5408\u306f\u4e88\u5f8c\u4e0d\u826f\u306e\u5146\u5019\u3068\u3055\u308c\u308b\uff08\u88681\uff09\u3002<\/p>\n

\u8868\uff11\uff1a\u5404\u7a2e\u75c7\u72b6\u304a\u3088\u3073\u305d\u306e\u767a\u751f\u983b\u5ea6\uff08Lancet Infect. Dis. 2014;14:763\u2013772. doi: 10.1016\/S1473-3099(14)70718-2.\uff09<\/p>\n

\n
\n
\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Symptom<\/td>\n\u60a3\u8005\u6570 (n)<\/td>\n\u75c7\u72b6\u3042\u308a (n, %)<\/td>\n<\/tr>\n
Fever<\/td>\n614<\/td>\n609 (99%)<\/td>\n<\/tr>\n
Fatigue<\/td>\n606<\/td>\n561 (93%)<\/td>\n<\/tr>\n
Anorexia<\/td>\n606<\/td>\n540 (89%)<\/td>\n<\/tr>\n
Malaise<\/td>\n337<\/td>\n274 (81%)<\/td>\n<\/tr>\n
Nausea<\/td>\n594<\/td>\n459 (77%)<\/td>\n<\/tr>\n
Myalgia<\/td>\n599<\/td>\n423 (71%)<\/td>\n<\/tr>\n
Abdominal pain \/ tenderness<\/td>\n335<\/td>\n183 (55%)<\/td>\n<\/tr>\n
Vomiting<\/td>\n588<\/td>\n308 (52%)<\/td>\n<\/tr>\n
Headache<\/td>\n601<\/td>\n308 (51%)<\/td>\n<\/tr>\n
Chill<\/td>\n508<\/td>\n316 (62%)<\/td>\n<\/tr>\n
Lymphadenopathy<\/td>\n331<\/td>\n166 (50%)<\/td>\n<\/tr>\n
Diarrhea<\/td>\n607<\/td>\n279 (46%)<\/td>\n<\/tr>\n
Arthralgia<\/td>\n328<\/td>\n80 (24%)<\/td>\n<\/tr>\n
Cough<\/td>\n572<\/td>\n165 (29%)<\/td>\n<\/tr>\n
Confusion<\/td>\n93<\/td>\n24 (26%)<\/td>\n<\/tr>\n
Sputum production<\/td>\n503<\/td>\n123 (24%)<\/td>\n<\/tr>\n
Throat congestion<\/td>\n81<\/td>\n10 (12%)<\/td>\n<\/tr>\n
Conjunctival congestion<\/td>\n90<\/td>\n10 (11%)<\/td>\n<\/tr>\n
Apathy<\/td>\n69<\/td>\n6 (9%)<\/td>\n<\/tr>\n
Petechiae \/ skin rash<\/td>\n328<\/td>\n30 (9%)<\/td>\n<\/tr>\n
Coma<\/td>\n69<\/td>\n4 (6%)<\/td>\n<\/tr>\n
Slurred speech<\/td>\n69<\/td>\n4 (6%)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

\u81e8\u5e8a\u691c\u67fb\u6240\u898b<\/h3>\n

\u672b\u68a2\u8840\u3067\u306f\u767d\u8840\u7403\u6e1b\u5c11\u304a\u3088\u3073\u8840\u5c0f\u677f\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002\u751f\u5316\u5b66\u691c\u67fb\u3067\u306fAST\u3001ALT\u3001LDH\u306e\u4e0a\u6607\u3001\u6d88\u5316\u5668\u75c7\u72b6\u306b\u4f34\u3046\u96fb\u89e3\u8cea\u7570\u5e38\u304c\u307f\u3089\u308c\u308b\u3002\u5c3f\u691c\u67fb\u3067\u306f\u8840\u5c3f\u3084\u86cb\u767d\u5c3f\u304c\u9ad8\u983b\u5ea6\u3067\u51fa\u73fe\u3059\u308b\u3002\u91cd\u75c7\u4f8b\u3067\u306f\u9aa8\u9ac4\u691c\u67fb\u306b\u304a\u3044\u3066\u7d30\u80de\u4f4e\u5f62\u6210\u3084\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u8840\u7403\u8caa\u98df\u50cf\u304c\u78ba\u8a8d\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3002<\/p>\n

\n

\u88682\uff0e\u8840\u6db2\u691c\u67fb\u6240\u898b(New Engl. J. Med. 2011;364:1523\u20131532. doi: 10.1056\/NEJMoa1010095.)<\/p>\n

\n
\n
\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Result<\/td>\nNormal level
\nno.\/total no. (%)<\/td>\n		Increased level
\nno.\/total no. (%)<\/td>\n		Decreased level
\nno.\/total no. (%)<\/td>\n<\/tr>\n
Platelet count<\/td>\n4\/73 (5)<\/td>\n0\/73<\/td>\n69\/73 (95)<\/td>\n<\/tr>\n
White-cell count<\/td>\n8\/74 (11)<\/td>\n2\/74 (3)<\/td>\n64\/74 (86)<\/td>\n<\/tr>\n
Neutrophil count<\/td>\n0\/12<\/td>\n0\/12<\/td>\n12\/12 (100)<\/td>\n<\/tr>\n
Lymphocyte count<\/td>\n2\/12 (17)<\/td>\n0\/12<\/td>\n10\/12 (83)<\/td>\n<\/tr>\n
Alanine aminotransferase<\/td>\n11\/64 (17)<\/td>\n53\/64 (83)<\/td>\n0\/64<\/td>\n<\/tr>\n
Aspartate aminotransferase<\/td>\n4\/63 (6)<\/td>\n59\/63 (94)<\/td>\n0\/63<\/td>\n<\/tr>\n
Ratio of albumin to globulin<\/td>\n11\/63 (17)<\/td>\n0\/63<\/td>\n52\/63 (83)<\/td>\n<\/tr>\n
Alkaline phosphatase<\/td>\n39\/53 (74)<\/td>\n3\/53 (6)<\/td>\n11\/53 (21)<\/td>\n<\/tr>\n
Lactate dehydrogenase<\/td>\n1\/51 (2)<\/td>\n49\/51 (96)<\/td>\n1\/51 (2)<\/td>\n<\/tr>\n
Creatine kinase<\/td>\n21\/49 (43)<\/td>\n25\/49 (51)<\/td>\n3\/49 (6)<\/td>\n<\/tr>\n
Creatine kinase MB fraction<\/td>\n19\/47 (40)<\/td>\n28\/47 (60)<\/td>\n0\/47<\/td>\n<\/tr>\n
Activated partial-thromboplastin time<\/td>\n7\/12 (58)<\/td>\n5\/12 (42)<\/td>\n0\/12<\/td>\n<\/tr>\n
Proteinuria<\/td>\n7\/43 (16)<\/td>\n36\/43 (84)<\/td>\n0\/43<\/td>\n<\/tr>\n
Hematuria<\/td>\n19\/46 (41)<\/td>\n27\/46 (59)<\/td>\n0\/46<\/td>\n<\/tr>\n
Fecal occult blood<\/td>\n15\/19 (79)<\/td>\n4\/19 (21)<\/td>\n0\/19<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

\u78ba\u5b9a\u8a3a\u65ad<\/strong><\/h3>\n

\u6025\u6027\u671f\u8840\u6db2\u304b\u3089\u306eVero\u7d30\u80de\u7b49\u3092\u7528\u3044\u305f\u30a6\u30a4\u30eb\u30b9\u5206\u96e2\u30fb\u540c\u5b9a\u3001\u3042\u308b\u3044\u306fRT-PCR\u6cd5\u306b\u3088\u308b\u30a6\u30a4\u30eb\u30b9\u907a\u4f1d\u5b50\u306e\u5897\u5e45\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3002**\u5c3f\u3084\u54bd\u982d\u306c\u3050\u3044\u6db2\u304b\u3089\u306e\u907a\u4f1d\u5b50\u691c\u51fa\u304c\u6709\u7528\u3067\u3042\u308b\u5834\u5408\u3082\u3042\u308b\u3002**\u307e\u305f\u3001\u6025\u6027\u671f\u3068\u56de\u5fa9\u671f\u306b\u304a\u3051\u308b\u6297SFTSV IgG\u6297\u4f53\u4fa1\u306e\u6709\u610f\u306a\u4e0a\u6607\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3082\u8a3a\u65ad\u306b\u6709\u7528\u3067\u3042\u308b\u3002<\/p>\n

\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\u304a\u3088\u3073\u5168\u56fd\u306e\u4fdd\u5065\u6240\u3067\u306fRT-PCR\u691c\u67fb\u4f53\u5236\u304c\u6574\u5099\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u4e00\u90e8\u65bd\u8a2d\u3067\u306f\u9593\u63a5\u86cd\u5149\u6297\u4f53\u6cd5\u3084ELISA\u6cd5\u306b\u3088\u308b\u6297\u4f53\u6e2c\u5b9a\u3082\u53ef\u80fd\u3067\u3042\u308b\u3002\u6b7b\u4ea1\u4f8b\u3067\u306f\u7d44\u7e54\u514d\u75ab\u67d3\u8272\u6cd5\u306b\u3088\u308a\u3001\u30ea\u30f3\u30d1\u7bc0\u306a\u3069\u306e\u81d3\u5668\u304b\u3089SFTSV\u6297\u539f\u3092\u691c\u51fa\u3057\u3066\u8a3a\u65ad\u3059\u308b\u3053\u3068\u3082\u53ef\u80fd\u3067\u3042\u308b\u3002SFTS\u7591\u3044\u4f8b\u3092\u8a3a\u5bdf\u3057\u305f\u5834\u5408\u306b\u306f\u3001\u4fdd\u5065\u6240\u306b\u76f8\u8ac7\u3059\u308b\u3068\u3088\u3044\u3002<\/p>\n

\u6cbb\u7642<\/h3>\n

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\u30d0\u30a4\u30aa\u30cf\u30b6\u30fc\u30c9\u5bfe\u7b56<\/h3>\n

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\u611f\u67d3\u75c7\u6cd5\u306b\u304a\u3051\u308b\u53d6\u308a\u6271\u3044<\/h3>\n

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\u53c2\u8003\u6587\u732e<\/h3>\n